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The mechanism-based rationale for concerns is strong, however, especially if applied to settings in which these peptides are used on a long-term basis [2, 24]

albicans group at the end of the experiment (Figures 3C,D)

Mechanisms underlying neuroprotection include enhanced cerebral angiogenesis supporting tissue oxygenation, anti-inflammatory effects reducing secondary injury, antioxidant activity limiting free radical damage, and modulation of neurotransmitter systems including the dopamine/glutamate/NO system