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As a result, studies suggest calorie intake may drop by up to 39%

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Food intake was recorded every 48 h (accounting for crumb spillage) beginning at dark cycle onset

Limitations of waiting 6 months before escalation The conventional approach of waiting 6 months before adjusting treatment strategies presents substantial drawbacks for GLP-1 non-responders

We do not know whether the effects are truly additive, partially redundant, or potentially counterproductive in some way