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Appendix A Definitions of Additive and Multiplicative Models Additive model (1) A model used in epidemiology, the structural form of which implies that the disease rate (R) is a linear function of an intercept term (), an exposure effect (E), and covariate effects (C): R = + E + C

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A striking depiction of a woman with bold makeup, eyes closed in a moment of relaxation as she enjoys a cigar