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The U.K., for example, banned packs of 10 in 2016

These habits may affect the activity of the mitochondrial respiratory chain as well as the replication and transcriptional regulation of mitochondrial genes, leading to altered mitochondrial function and, in turn, to psychiatric disorders 59

Many vape store owners fear for the survival of their businesses under the severity of state actions banning the sale of e-cigarettes, which arguably make up a majority of their sales

By Poverty Level: 33% At or above poverty, 48% below poverty

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Figure 1 Proportion of countries with or without electronic cigarette regulation or ban, categorized by WHO region and World Bank income classification Bivariate logistic regression showed countries outside Africa had significantly higher odds of having e-cigarette regulations: nearly six times in South-East Asia, four times in the Americas and Western Pacific, and three times (not significant) in the Eastern Mediterranean