Elle diffre de la forme de supplment courante, la cyanocobalamine, qui porte un groupe cyanure et doit tre convertie mtaboliquement avant utilisation, et de lhydroxocobalamine, une forme intermdiaire
doi:10.3390/molecules27217167 Available from Rinnerthaler M, Bischof J, Streubel MK, Trost A, Richter K
Use only under medical supervision, particularly prior to surgery, to reduce risks
The concentration was 50 to 100 times lower than standard GHK-Cu serums (0.02% vs 1 to 2%), which likely explains the modest outcome
Abbreviations GSH: l-glutathione ATP: adenosine triphosphoric acid -GCS: -glutamylcysteine synthetase GS: glutathione synthetase GGT: -glutamyltranspeptidase PepT: tripeptidase CD: cysteine desulfhydrase CBL: -lyase GBE: glycogen-branching enzyme l-SDs: l-serine deaminases PK: pyruvate kinase PEP: phosphoenolpyruvic acid G6P: glucose 6-phosphate F6P: fructose 6-phosphate PFK: phosphofructose kinase IPTG: isopropyl -D-1-thiogalactopyranoside DCW: dry cell weight 2-DE: two-dimensional electrophoresis TCA: trichloroacetic acid CBB: coomassie brilliant blue EMP: embden meyerhof pathway References Meister A, Anderson ME
Guideline 4: Laboratory Monitoring and Dose Adjustments Laboratory monitoring is key in checking how well B12 treatment works