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The binding of nicotine, as well as any other type of nAChR agonist, can alter the synaptic release of acetylcholine itself, as well as a wide range of other neurotransmitters such as dopamine, norepinephrine, serotonin, and glutamate

doi:10.1001/jama.284.18.2348

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Mutat Res 751:3439 Goldhirsch A, Winer EP, Coates AS, Gelber RD, Piccart-Gebhart M, Thrlimann B, Senn HJ (2013) Panel members Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer