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Smoking during pregnancy has been linked to both short-term and long-term problems, such as preterm birth and intellectual impairment

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[1] Neurosyphilis and ocular syphilis may also be present during this stage and others, depending on the initial point of infection: Neurosyphilis The infection spreads to the brain and spinal cord and may lead to meningeal syphilis (headache, stiff neck, nausea, and vomiting), meningovascular syphilis (headache, stiff neck, nausea, vomiting, and risk of stroke), general paresis (personality or mood changes), or tabes dorsalis (muscle failure and pain and impaired balance)

This made sense, and the highest rated cigars in Cigar Aficionado were always aged Cubans