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It may also be a sign of other hormonal and autoimmune conditions, and rarely cancer
A receptor first understood as a pancreatic switch for insulin turned out to sit across circuits that govern reward, memory, mood, and movement, and the drugs that engage it have become some of the most-studied molecules in medicine
Regulatory authorities advise assessing how renal and hepatic impairment affects the pharmacokinetics of new drugs, as this evaluation may indicate the need for dose adjustment in these populations [12,13,14,15]
[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Liu J., Aylor K.W., Liu Z
Mol Cancer Res (2005) 3(11):60715