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Saliva Collection, Preparation, and UPLC-MS Sixteen saliva samples were collected for the metabolomic analysis using ultraperformance liquid chromatographymass spectrometry (UPLC-MS), comprising of 11 samples from healthy individuals and five samples from OSCC patients ( Supplementary Table S1 )

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Inadequate repair of sperm DNA damage might lead to major mutations which can be inherited from one generation to the next and can take many different forms, ranging from structural alterations to single nucleotide variations and insertions/deletions (indels) [89]

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They found that adults and children who were exposed to tobacco smoke, either from heated tobacco products (HTPs) or conventional cigarettes, showed markers of oxidative stress and endotoxemia

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