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Indeed, while nicotine in normal doses is not as dangerous as perceived, the Surgeon Generals report in 2014, The Health Consequences of Smoking50 Years of Progress, surmised that nicotine has acute toxicity at high doses and activates biological pathways that upsurge the risk of disease

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Compared with placebo, the likelihood of quitting smoking was roughly doubled with NRT (1.84, 95% CI 1.711.99) and bupropion (1.82, 1.602.06) and was improved further with varenicline (2.88, 2.403.47) (Cahill et al., 2013)

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It did almost nothing to help me put the puzzle pieces together once the movie was over