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CYP1A1 metabolic activity has also been shown to be increased by approximately 66%70% in smokers, mainly due to exposure to aryl hydrocarbons such as benzo [a]pyrene (Vistisen, Loft, and Poulsen, 1991)

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Use of smokeless tobacco can cause mouth cancer, gum disease, and tooth loss

Some Canadian tobacco farmers subject the tobacco leaves to air curing or the process of leaving the leaves in a well-ventilated barn to dry

Medical tests can detect nicotine in peoples urine, blood, saliva, hair, and nails