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Although each example may stand as an isolated, individual event, in reality these results are systemic

Topography of reward and aversion encoding in the mesolimbic dopaminergic system

Long-term complications may include muscle weakness, osteoporosis, cataracts, glaucoma and ulcers

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We cannot yet be sure what impact they will have on smoking rates or population health, whether they'll be the miracle product or not." However, researchers at Public Health England now say that e-cigarettes are 95 per cent safer than conventional cigarettes and, though not risk-free, "have the potential to make a significant contribution to the endgame for tobacco"