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Limited long-term human studies

A 2025 Kinsey study showed that 18% of respondents said their sexual desire had increased on GLP-1s while 16% said it had decreased

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Compounded versus brand-name semaglutide: reconstitution differences Not all semaglutide is created equal, and the reconstitution process differs significantly depending on which form you are working with

Although a significant lowering of serum p-CS and p-cresol glucuronide concentrations was not observed, the authors reported an apparent downward decline in the treated rats (Dong et al., 2024)

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