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However, only a small number of patients were included in the study, and median levels were not elevated even before the commencement of GLP-1 RAs treatment (102)

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Review of childhood obesity: from epidemiology, etiology, and comorbidities to clinical assessment and treatment

59 Recently, the SURMOUNT-5 trial demonstrated that tirzepatide was superior to semaglutide in obese patients without diabetes with respect to reductions in body weight and waist circumference at week 72

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Second, it provides a rationale for the lack of a single causative gene for hEDS