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an overview

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We can't stress this enough: careful measurement is the bedrock of responsible science

A growing body of translational research suggests that IN delivery can achieve CNS therapeutic effects while minimizing systemic exposure, allowing patients to experience fewer adverse effects, such as anemia or gastrointestinal upset, which are common concerns with oral or intravenous chelators

To minimize potential contamination from minor neuronal signals, an arbitrary boundary was defined around each astrocyte based on its characteristic morphology, including visible processes and branches