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Additionally, L-glutathione or reduced glutathione contributes to lightening and melanin production inhibition.

Deboever N, Eisenberg M, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth J, Sepesi B, Swisher SG , Vaporciyan AA, Walsh GL, Antonoff MB

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Furthermore, a decrease in the nuclear expression of p jun N-terminal kinase (JNK), p-p38, pIB, and P65 was observed in western blot analysis

Clinical efficacy and mechanism of action are pharmacologically equivalent, though compounded formulations are not FDA-approved as branded products