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If ongoing trials continue to deliver positive results, triple agonist therapies for diabetes may represent the next major evolution in treating obesity, type 2 diabetes, and related metabolic diseases
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For example, spatial transcriptomic analysis of the mouse brain revealed that depression is closely linked to gene expression changes in specific regions, including the hippocampus, isocortex, and amygdala
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They would also need to be modified so that they can stay in the bloodstream long enough to be effective, which Pentelutes lab is also working on