Baseline and interval laboratory monitoring should include: fasting glucose and HbA1c (tirzepatide can cause hypoglycemia in non-diabetic subjects if caloric intake drops too low), lipase and amylase (pancreatitis risk with GLP-1 agonists), liver function tests (AST, ALT, bilirubin), and thyroid panel (TSH, free T3, free T4)
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The PCAC is an advisory body
Retatrutide (a triple GIP/GLP-1/glucagon receptor agonist), survodutide, mazdutide, and CagriSema represent the next generation of anti-obesity compounds that may offer even greater efficacy or better tolerability profiles
Testosterone cypionate is the most relatively affordable option
For pediatric patients, we recommend focusing on foundational health strategies such as proper nutrition, gut support, and lifestyle modifications to promote overall well-being