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Acute toxicity to Daphnia magna neonates Daphnia magna is highly sensitive to aquatic toxicants, which is recognized as an internationally standardized indicator organism for evaluating the ecological safety of nanomaterials in aquatic environments [52]

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Fleiss JL, Tytun A, Ury HK (1980) A simple approximation for calculating sample sizes for comparing independent proportions

Toxicol Lett 197: 5159, 2010