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But every single ADR report can contribute to: Better patient safety Stronger drug safety databases Early signal detection Safer prescribing practices Improved public health decisions

Our results confirmed these findings

In a phase 3, double-blind, randomized, controlled trial, 2,539 adults with a body-mass index (BMI) of 30 or greater, or 27 or greater with at least one weight-related complication, were given weekly subcutaneous injections of tirzepatide (5 mg, 10 mg, or 15 mg) or a placebo for 72 weeks

They work through overlapping mechanisms and combining them would significantly increase side effect risks without proven additional benefits

However, their effectiveness can vary depending on individual patient factors such as baseline HbA1c, weight, other health conditions, and treatment adherence

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